Fibrodysplasia Ossificans Progressiva (FOP) Epidemiology
Press Release

DelveInsight launched a new report on Fibrodysplasia Ossificans Progressiva (FOP) – Epidemiology Forecast to 2030.

DelveInsight’s ‘Fibrodysplasia Ossificans Progressiva (FOP) – Epidemiology Forecast‘ report delivers an in-depth understanding of the disease, historical and forecasted Fibrodysplasia Ossificans Progressiva (FOP) epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside the skeleton (extra-skeletal or heterotopic bone) that constrains movement. This process generally becomes noticeable in early childhood, starting with the neck and shoulders, and proceeding down the body and into the limbs.

Mutations in the ACVR1 gene causes fibrodysplasia ossificans progressiva. The underlying genetic mutation in FOP alters the signals that regulate the induction of cell differentiation leading to bone formation.

The symptoms begin in the first decade of life with episodes of painful inflammatory soft tissue swellings. Gradually, there occurs restriction of motion at various joints, severely limiting the activities of daily living and the quality of life of such patients by the third decade of life.

Extra-skeletal bone formation causes a progressive loss of mobility as the joints become affected. Inability to fully open the mouth may cause difficulty in speaking and eating. Over time, people with this disorder may experience malnutrition due to their eating problems. They may also have breathing difficulties as a result of extra bone formation around the rib cage that restricts expansion of the lungs.

“In the United States, the females were affected more as compared to males in 2017.”

Scope of the Report:
1. The Fibrodysplasia Ossificans Progressiva (FOP) report covers a detailed overview explaining its causes, symptoms, classification, pathophysiology, diagnosis and treatment patterns
2. The Fibrodysplasia Ossificans Progressiva (FOP) Epidemiology Report and Model provide an overview of the risk factors and global trends of Fibrodysplasia Ossificans Progressiva (FOP) in the seven major markets (7MM:US, France, Germany, Italy, Spain, UK, and Japan)
3. The report provides insight about the historical and forecasted patient pool of Fibrodysplasia Ossificans Progressiva (FOP) in seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan
4. The report helps to recognize the growth opportunities in the 7MM with respect to the patient population
5. The report assesses the disease risk and burden and highlights the unmet needs of Fibrodysplasia Ossificans Progressiva (FOP)
6. The report provides the segmentation of the Fibrodysplasia Ossificans Progressiva (FOP) epidemiology

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Reasons to buy:
1. The Fibrodysplasia Ossificans Progressiva (FOP) Epidemiology report will allow the user to –
2. Develop business strategies by understanding the trends shaping and driving the global Fibrodysplasia Ossificans Progressiva (FOP) market
3. Quantify patient populations in the global Fibrodysplasia Ossificans Progressiva (FOP) market to improve product design, pricing, and launch plans
4. Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for Fibrodysplasia Ossificans Progressiva (FOP) therapeutics in each of the markets covered
5. Understand the magnitude of Fibrodysplasia Ossificans Progressiva (FOP) population by its epidemiology
6. The Fibrodysplasia Ossificans Progressiva (FOP) Epidemiology Model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based with transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over 11-year forecast period using reputable sources

Table of contents:
1. Key Insights
2. Executive Summary of Fibrodysplasia Ossificans Progressiva (FOP)
3. Fibrodysplasia Ossificans Progressiva (FOP): Disease Background and Overview
4. Patient Journey
5. Epidemiology and Patient Population
6. Treatment Algorithm, Current Treatment, and Medical Practices
7. KOL Views
8. Unmet Needs
9.  Appendix
10. DelveInsight Capabilities
11. Disclaimer

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